SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.6
USERS' SCORE
Moderately Good
Based on 11 Reviews
7.3
Supplement Facts
Serving Size: 2 Gummy Supplements
Amount Per Serving
%DV
Calories
15
 
Total Carbohydrate
3 g
1%†
Total Sugars
3 g
**
Includes 3 g Added Sugars
 
6%†
Melatonin
5 mg
**

Top Medical Research Studies

9.5
Melatonin improves sleep apnea outcomes
Effect of melatonin on insomnia and daytime sleepiness, in patients with obstructive sleep apnea and insomnia (COMISA): A randomized double-blinded placebo-controlled trial.
Relevant and promising findings
We investigated how melatonin affects patients with obstructive sleep apnea and insomnia. In a double-blind trial, thirty patients received either 10 mg of melatonin or a placebo for a month.

The results were striking; those taking melatonin reported better sleep quality, less daytime sleepiness, and greater adherence to their PAP devices. Improvements were noted across several assessments: the Pittsburgh Sleep Quality Index, Insomnia Severity Index, Epworth Sleepiness Scale, and Functional Outcomes of Sleep Questionnaire showed significant gains for the melatonin group.

Thus, melatonin appears to be a promising option to enhance sleep quality and treatment compliance in this challenging patient group.
Read More
7
Agomelatine shows promise for OSA
Evaluating the Effects of Agomelatine on Polysomnography Parameters in Patients with Obstructive Sleep Apnea.
Moderate relevance to sleep therapies.
We conducted a study to see if agomelatine, a melatonin-based drug, could help patients with obstructive sleep apnea (OSA). In this randomized and single-blind trial, seventy adults took either agomelatine or a placebo for three nights before sleep testing.

The results showed that agomelatine improved total sleep time, sleep efficiency, and reduced waking percentage compared to the control group. However, other sleep parameters did not show significant changes. Overall, agomelatine may be beneficial for those struggling with OSA.
Read More
7
Melatonin's role in sleep apnea
Melatonin mediates intestinal barrier dysfunction and systemic inflammation in moderate-severe OSA patients.
Significance of melatonin in OSA
We explored how melatonin, known for its anti-inflammatory properties, interacts with obstructive sleep apnea (OSA) and related health issues.

In a study of 235 men experiencing sleep problems, we found that higher OSA severity correlated with lower melatonin levels and increased markers of intestinal barrier dysfunction and inflammation.

Melatonin appeared to mediate these relationships, explaining a significant portion of the connection between apnea severity and these harmful conditions. However, the overall results suggest that while melatonin is connected to inflammation and intestinal issues in OSA, it does not appear to solve these complications.
Read More

Most Useful Reviews

9.5
Serene bedtime
My 10-year-old son with ADHD now falls asleep peacefully without anxiety, leading to better management of his sleep apnea. We no longer experience breakdowns before bed, and he wakes up energised. This product came highly recommended by his Australian paediatrician.
Read More
9.5
Effective sleep aid
Best choice for dealing with sleep apnea. After taking melatonin, I no longer need sleeping pills, reducing my body's burden. It’s wonderful.
Read More
9.5
Deep sleep achieved
It works wonderfully, allowing for deep sleep, which helps with sleep apnea. I will continue purchasing.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.6
  • All Researches
9.5
Melatonin improves sleep apnea outcomes
Effect of melatonin on insomnia and daytime sleepiness, in patients with obstructive sleep apnea and insomnia (COMISA): A randomized double-blinded placebo-controlled trial.
Relevant and promising findings
We investigated how melatonin affects patients with obstructive sleep apnea and insomnia. In a double-blind trial, thirty patients received either 10 mg of melatonin or a placebo for a month.

The results were striking; those taking melatonin reported better sleep quality, less daytime sleepiness, and greater adherence to their PAP devices. Improvements were noted across several assessments: the Pittsburgh Sleep Quality Index, Insomnia Severity Index, Epworth Sleepiness Scale, and Functional Outcomes of Sleep Questionnaire showed significant gains for the melatonin group.

Thus, melatonin appears to be a promising option to enhance sleep quality and treatment compliance in this challenging patient group.
Read More
7
Melatonin's role in sleep apnea
Melatonin mediates intestinal barrier dysfunction and systemic inflammation in moderate-severe OSA patients.
Significance of melatonin in OSA
We explored how melatonin, known for its anti-inflammatory properties, interacts with obstructive sleep apnea (OSA) and related health issues.

In a study of 235 men experiencing sleep problems, we found that higher OSA severity correlated with lower melatonin levels and increased markers of intestinal barrier dysfunction and inflammation.

Melatonin appeared to mediate these relationships, explaining a significant portion of the connection between apnea severity and these harmful conditions. However, the overall results suggest that while melatonin is connected to inflammation and intestinal issues in OSA, it does not appear to solve these complications.
Read More
7
Agomelatine shows promise for OSA
Evaluating the Effects of Agomelatine on Polysomnography Parameters in Patients with Obstructive Sleep Apnea.
Moderate relevance to sleep therapies.
We conducted a study to see if agomelatine, a melatonin-based drug, could help patients with obstructive sleep apnea (OSA). In this randomized and single-blind trial, seventy adults took either agomelatine or a placebo for three nights before sleep testing.

The results showed that agomelatine improved total sleep time, sleep efficiency, and reduced waking percentage compared to the control group. However, other sleep parameters did not show significant changes. Overall, agomelatine may be beneficial for those struggling with OSA.
Read More
7
REM Sleep Behavior Disorder Overview
REM sleep behavior disorder as a complex condition with heterogeneous underlying disorders: clinical management and prognostic implications [Commentary].
Highly relevant clinical insights
We explored REM sleep behavior disorder (RBD) as a complex condition that can be linked to a variety of underlying disorders. Through a literature review and insights from foundational texts, we recognized that RBD may emerge at any age and can initially appear as an isolated issue or be associated with other significant conditions like Parkinson’s and narcolepsy.

Our findings highlighted that effective management often includes melatonin or clonazepam as treatment options. Furthermore, ongoing research into the connections between RBD and other sleep disorders, such as obstructive sleep apnea, remains vital for enhancing diagnostics and treatment strategies.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 11 Reviews
7.3
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9.5
Serene bedtime
My 10-year-old son with ADHD now falls asleep peacefully without anxiety, leading to better management of his sleep apnea. We no longer experience breakdowns before bed, and he wakes up energised. This product came highly recommended by his Australian paediatrician.
9.5
Effective sleep aid
Best choice for dealing with sleep apnea. After taking melatonin, I no longer need sleeping pills, reducing my body's burden. It’s wonderful.
9.5
Deep sleep achieved
It works wonderfully, allowing for deep sleep, which helps with sleep apnea. I will continue purchasing.
9
Restful nights
I’m on my second jar. It works well for reducing sleep apnea without causing habituation. I even slept well without it once. After trying another brand, I realised how much I needed VitaFusion, so I ordered more.
6.3
Improves sleep quality
This was my first time trying it, and I found it helpful for sleep, especially with jet lag. It’s nice and chewy.

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